Translational EEG solutions
The electrical activity of neuronal networks underpins brain activities and cognitive processes and can be evaluated and quantified through the use of electroencephalography, or EEG. The EEG profile is one of the most conserved phenotypes throughout evolution* and the same parameters can be recorded from rodent, non-human primates and humans. Thus, modifications correlating with pathological conditions can be detected in most neurological and psychiatric disorders across different species**. Conserved electro-physiological endpoints revealed by EEG can therefore be used to study most CNS disorders.
SynapCell’s translational solutions reveal the efficacy of your candidate drugs in neurological and psychiatric disorders by using surface and deep EEG and related technologies, together with intelligently selected relevant animal models, and protocols performed in the conditions used in clinical trials.
Since 2005, SynapCell has successfully developed and launched translational drug discovery and development solutions for epilepsy and is recognized as an expert partner by international drug manufacturers. The relevance of the results obtained and the feedback from our customers have convinced us to deploy this approach to drug discovery for other CNS disorders. Please contact us for more information.
* Scaling brain size, keeping timing: evolutionary preservation of brain rhythms. Buzsáki G et al., 2013.
** Aligning strategies for using EEG as a surrogate biomarker: a review of preclinical and clinical research, Leiser et al., 2011.