ESSENTIAL
TREMOR

Once known as familial tremor, benign tremor or hereditary tremor, essential tremor (ET) is a neurological condition that causes a rhythmic trembling of the hands, head, voice, legs or trunk. Some people even feel an internal shake. ET is often confused with Parkinson’s disease although it’s eight times more common, affecting an estimated 10 million Americans and millions more worldwide. But essential tremor is more than just a tremor. Because of stereotypes and a lack of awareness, many people with ET never seek medical care.

The International Essential Tremor Foundation

Not so many
Treatment options

  • To date no medication specifically designed to treat essential tremor exist.
  • Several medications can be used to treat the symptoms, including Propranolol.
  • However, a series of undesirable effects are affecting treated patients.
  • There is therefore a huge need for novel medications to treat ET patients.
  • AntiEpileptic Drugs (AEDs) such as Gabapentin or Topiramate have also been used to treat the disorder.
  • Novel AEDs could be promising treatment options in the near future.

Essential Tremor model
Decide. From inside.

  • Cue® is applied to objectively measure brain activity on our Essential Tremor model.
  • Induced by harmaline, the ET mouse shows specific and stable oscillatory activities.
  • Such oscillations have been successfully reversed by propranolol, currently used to treat ET patients.
  • Cue® can reach any brain structure. ET signatures are monitored in the motor cortex or in the cerebellum upon request.