Modified electrical activity in neuronal networks is symptomatic of a wide range of CNS disorders. SynapCell’s team has expertise in identifying and deciphering these signals, giving you access to the most accurate translational drug discovery tools.
HOW IT WORKS
We measure the electrical activity of neuronal networks by recording local field potentials (LFP). We register different forms of electrical activities, using a wide range of advanced EEG-based recording and processing techniques to give you a precise answer to your specific question.
Making clear and better-informed decisions.
Since 2005 we have been developing Cue®, which core technology can predict in-human efficacy of a lead candidate, at the preclinical step. EEG-based and patient inspired, Cue® is the smart combination of a team with specific skillsets in Neuroscience, translational rodent models, high-end recording techniques and proprietary signal processing. SynapCell’s technology measures specific oscillatory activities from any brain structure. Known to be altered in CNS disorders and highly conserved across species, these EEG biomarkers are used to determine the effect of a given molecule on brain function.
To your specific question, Cue® offers a series of pharmacodynamic assays for:
- Lead selection (screening of small libraries of compounds)
- Lead validation (dose-response effect, pharmacokinetics)
- Disease-Modifying potential
- Antiepileptogenic effect
- Model phenotyping
- De-risking (pro-epileptic effect)
- Dose optimizing and much more…
Having Dormant EEG Data on your servers?
What if you had a treasure that’s hidden down there?
Cue® can run any of your past EEG recordings to deliver precise outcomes in a full comprehensive report so you can benefit from our expertise in analysis and pharmacology understanding.