Mesio-Temporal Lobe Epilepsy (MTLE)
Also called Focal, Drug-refractory or Drug-resistant epilepsy, Mesio-Temporal Lobe Epilepsy (MTLE) is an epileptic condition for which no effective nor satisfactory treatment exists to date.
With over 10% of the total epileptic population affected, MTLE is a major challenge for patients as most pharmacological treatments have no effect on these seizures.
How about addressing the disease with a preclinical model that mimicks human MTLE?
clinically-relevant model of mtle
Pr. Karen S. Wilcox, Chair of Pharmacology and Toxicology at University of Utah
We find in SynapCell a predictive rodent model of therapy-resistant MTLE that supplements our evaluation capabilities and addresses an important recommendation of the NINDS Working Group.